CARDIAC CHANGES DURING PROGRESSIVE HYPOTHERMIA

Abstract
In hypothermia produced in rats and kittens without anesthesia there is a linear relationship between the decrease in heart rate and the lowering of the body level of heat. Body temps. as low as 75[degree]F are not critical, although there is slowing of the heart to 1/3 the normal rate, and increase in the conduction time and in the width and amplitude of R and T waves. Temps. of 65oF or less are critical; the rhythm becomes irregular, the P-R interval lengthens, and A-V block appears. In kittens there develops a peculiar long diphasic ventricular wave. The cardiac changes are reversible, disappearing as recovery proceeds. Cold has a direct effect upon the heart, but the vascular debilities incident to hypothermia are suggested to be secondary to anoxemia induced by cold narcosis of the medullary respiratory centers.

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