Putative pheromone receptors related to the Ca 2+ -sensing receptor in Fugu
- 28 April 1998
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 95 (9) , 5178-5181
- https://doi.org/10.1073/pnas.95.9.5178
Abstract
By a combination of PCR with degenerate primers and low stringency probing, we have isolated a large family of genes related to the Ca 2+ -sensing receptor from the genome of Fugu rubripes . One of the genes (type I) is the Fugu homologue of the Ca 2+ -sensing receptor. The remaining genes can be divided into five classes (type II–VI) on the bases of gene structure. In several types, the genes occur in clusters as tandem arrays. These genes appear to be the homologues of the vomeronasal pheromone receptors recently described in rodents. The Fugu genes are expressed in the tissues of the nose, suggesting that they may have a similar physiological role.Keywords
This publication has 10 references indexed in Scilit:
- Caloramator viterbensis sp. nov., a novel thermophilic, glycerol-fermenting bacterium isolated from a hot spring in ItalyInternational Journal of Systematic and Evolutionary Microbiology, 2002
- A New Multigene Family of Putative Pheromone ReceptorsNeuron, 1997
- A Novel Family of Putative Pheromone Receptors in Mammals with a Topographically Organized and Sexually Dimorphic DistributionCell, 1997
- A Multigene Family Encoding a Diverse Array of Putative Pheromone Receptors in MammalsCell, 1997
- Isolation, Characterization and Evolution of Nine Pufferfish (Fugu rubripes) Actin GenesJournal of Molecular Biology, 1996
- Tetrodotoxin as a pheromoneNature, 1995
- A novel family of genes encoding putative pheromone receptors in mammalsCell, 1995
- Mutations in the human Ca2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidismCell, 1993
- A novel multigene family may encode odorant receptors: A molecular basis for odor recognitionCell, 1991
- The neighbor-joining method: a new method for reconstructing phylogenetic trees.Molecular Biology and Evolution, 1987