Nanocrystalline epsein–barr virus decoys

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Abstract
A novel biotechnology is introduced by way of the successful synthesis of nanocrystalline Epstein–Barr virus (EBV) decoys having specific in vivo immunogenie activity. Assembled from ultrafine suface modified tin oxide and purified DNA‐free isolated EBV envelope proteins, the decoys consisted of >150 nm units whose electophoretic mobilities were similar to whole EBV; whose outer coats were strongly immunoreactive with murine monoclonal anti‐EBV antibodies; and which elicited immunospecific niutralizing anti‐EBV antibodies in the rabbit. The development of this carier techonology for vaccine preparations is suggested.