Adrenal Corticosteroids Enhance Production of Type-C Virus Induced by 5-Iodo-2′-Deoxyuridine from Cultured Mouse Fibroblasts
- 1 August 1973
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 70 (8) , 2391-2395
- https://doi.org/10.1073/pnas.70.8.2391
Abstract
Induction of RNA “tumor” viruses by 5-iodo-2′-deoxyuridine in mouse fibroblasts is stimulated 5- to 25-fold by glucogenic adrenal corticosteroids. Enhancement of virus production by the hormones is inhibited by low concentration of cordycepin, an inhibitor of poly(A) synthesis.Keywords
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