POTENTIAL PHARMACOTHERAPY OF ALZHEIMER DISEASE. A COMPARISON OF VARIOUS FORMS OF PHYSOSTIGMINE ADMINISTRATION
- 1 June 1988
- journal article
- clinical trial
- Published by Wiley in Acta Neurologica Scandinavica
- Vol. 77 (s116) , 19-32
- https://doi.org/10.1111/j.1600-0404.1988.tb07983.x
Abstract
This paper reviews clinical trials with physostigmine administered to Alzheimer patients using three different routes of administration: oral, i.v. and intracerebroventricular (i.c.v.). It compares results obtained with three different routes by the authors as well as by other authors. Particular emphasis is given to a novel type of physostigmine administration, the i.c.v. route. Advantages and disadvantages, as well as side effects of each route are presented and discussed.Keywords
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