THE PHOTODYNAMIC INACTIVATION OF PHAGE PRECURSOR BY METHYLENE BLUE
Open Access
- 19 July 1940
- journal article
- research article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 23 (6) , 705-708
- https://doi.org/10.1085/jgp.23.6.705
Abstract
Methylene blue added to suspensions of activated staphylococci in amounts sufficient to furnish 1 x 105 molecules of dye/bacterium inactivates the phage precursor content of the cells without causing cell death when the mixtures are exposed to strong light of 4000–8000 Å. There is a lag phase of approximately 15 minutes in the photodynamic inactivation of phage precursor by methylene blue. This delay seems to be due to a primary reaction between the cell and methylene blue after the completion of which exposure to light brings about the inactivation of precursor quite promptly.This publication has 0 references indexed in Scilit: