OSTEITIS DEFORMANS WITH ANGIOID STREAKS

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Abstract
Paget1in 1877 reported on a form of chronic inflammation of the bones. He ascribed the name osteitis deformans to this disease. The patient described by Paget, in addition to having skeletal changes, had become somewhat deaf, and the "sight was partially destroyed by retinal hemorrhage first in one eye then in the other." Osier2found Paget's disease of the bone in 2 of 20,000 patients examined at the Johns Hopkins Hospital. Schmorl3discovered definite microscopic evidence of osteitis deformans in 3 per cent of 4,614 autopsies performed on persons over 39 years of age. Paget's disease of the bone is therefore rarely seen clinically but appears frequently as a subclinical entity. The characteristic eyeground appearance of what is now known as angioid streaks was first described and illustrated by Doyne4in 1889. Two years later Plange5described a case. Knapp6in 1892 cited

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