The VKVI Subgroup of Rabbit Light Chains: Complete Amino Acid Sequence of a Third Variable Region (K29–213)
- 1 February 1979
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 9 (2) , 105-114
- https://doi.org/10.1111/j.1365-3083.1979.tb02712.x
Abstract
The amino acid sequence of the variable region of a rabbit anti-streptococcal A-variant antibody [Ab] L chain was determined. By using a combination of different cleavage methods, the sequence was established. Large peptides were sequenced in an extensively modified Beckman sequenator. L chain K29-213 belongs to a rare subgroup (.kappa.VI). Several of these L chains of Ab with different specificities were totally or partially sequenced. Comparison of these L chains reveals at least 4 germ-line-encoded variants within this subgroup.Keywords
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