Diastereoselective 1,4-Addition Reactions of Bis(iodozincio)ethane toα,β-Unsaturated Ketones

31 December 2000

journal article
letter
Published by Georg Thieme Verlag KG in Synlett

Vol. 2000 (08) , 1202-1204
https://doi.org/10.1055/s-2000-6763

Abstract

Conjugate addition of 1,1-bis(iodozincio)ethane to chalcone in presence of chlorotrimethylsilane proceeded diastereoselectively to produce the corresponding silyl enolate of γ-iodozincioketone.

Keywords

4-ADDITION
SILYL ENOLATE
COPPER
DIASTEREOSELECTIVE
COUPLING