STRESS STUDIES IN THE ECZEMA-ASTHMA-HAY-FEVER DIATHESIS

Abstract
IN A PREVIOUS paper1 we reported the effects of an artificially applied stress situation on the "alarm reaction" response of persons with the skin component of the eczema-asthma-hay-fever complex (atopic dermatitis). While the number of patients studied was small, there were definite indications of an abnormal response, as measured by the eosinopenic index and changes in the lymphocyteneutrophile ratio. Our results supported Selye's concept2 that the allergic or atopic diathesis should be included in the so-called diseases of adaptation. This concept holds that these diseases may depend largely upon a derangement of the pituitary-adrenocortical response to stress, and, further, that as for "triggering" the alarm reaction, there is little or no difference between physical and psychic or emotional stress. In this paper we are reporting a continuation of our previous studies. Both our control and experimental groups have been considerably expanded. The alarm-reaction response, as

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