Phytophthora Genome Sequences Uncover Evolutionary Origins and Mechanisms of Pathogenesis
Top Cited Papers
- 1 September 2006
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 313 (5791) , 1261-1266
- https://doi.org/10.1126/science.1128796
Abstract
Draft genome sequences have been determined for the soybean pathogen Phytophthora sojae and the sudden oak death pathogen Phytophthora ramorum. Oömycetes such as these Phytophthora species share the kingdom Stramenopila with photosynthetic algae such as diatoms, and the presence of many Phytophthora genes of probable phototroph origin supports a photosynthetic ancestry for the stramenopiles. Comparison of the two species' genomes reveals a rapid expansion and diversification of many protein families associated with plant infection such as hydrolases, ABC transporters, protein toxins, proteinase inhibitors, and, in particular, a superfamily of 700 proteins with similarity to known oömycete avirulence genes.Keywords
This publication has 29 references indexed in Scilit:
- Novel phosphatidylinositol phosphate kinases with a G-protein coupled receptor signature are shared by Dictyostelium and PhytophthoraTrends in Microbiology, 2006
- Trafficking arms: oomycete effectors enter host plant cellsPublished by Elsevier ,2006
- Subfamilies of cpmA, a gene involved in circadian output, have different evolutionary histories in cyanobacteriaMicrobiology, 2006
- Phylogenomic Analysis Identifies Red Algal Genes of Endosymbiotic Origin in the ChromalveolatesMolecular Biology and Evolution, 2005
- An ancestral oomycete locus contains late blight avirulence gene Avr3a , encoding a protein that is recognized in the host cytoplasmProceedings of the National Academy of Sciences, 2005
- Differential Recognition of Highly Divergent Downy Mildew Avirulence Gene Alleles by RPP1 Resistance Genes from Two Arabidopsis LinesPlant Cell, 2005
- Large-Scale Gene Discovery in the OomycetePhytophthora infestansReveals Likely Components of Phytopathogenicity Shared with True FungiMolecular Plant-Microbe Interactions®, 2005
- Targeting Malaria Virulence and Remodeling Proteins to the Host ErythrocyteScience, 2004
- Migration of the Plastid Genome to the Nucleus in a Peridinin DinoflagellateCurrent Biology, 2004
- Phytotoxic Protein PcF, Purification, Characterization, and cDNA Sequencing of a Novel Hydroxyproline-containing Factor Secreted by the Strawberry Pathogen Phytophthora cactorumJournal of Biological Chemistry, 2001