Abstract
Improved methods of extracting vincaleucoblastin from leaves and tissue cultures of Catharanthus roseus and of the quantitative determination of this dimeric indole-alkaloid by reflectance densitometry of TLC-plates have been established. Approximately 0.05% VLB were found in the leaves and, using high-performance-thin-layer-chromatography, 0.00013% VLB in callus cultures (not in suspension cultures!) derived from this plant

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