Alterations in Sindbis Viral Envelope Proteins by Treating BHK cells with Glucosamine

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Abstract
Addition of d -glucosamine to BHK cells infected with Sindbis virus inhibited the formation of the E-2 viral envelope from its precursor PE-2. Release of virus was blocked, and two new viral protein bands replaced the normal envelope protein bands detected in SDS-gel electropherograms of infected cell extracts.