Effect of Light on Urinary Coproporphyrin Excretion in Lead-Poisoned Rabbits.

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Abstract
Five rabbits injd. intraperit. with 100 mg./kg. of Pb acetate and kept in complete darkness excreted within 2 wks. an avg. of approx. 80 [mu]g. of coproporphyrin per day. (Control values were 5-10 [mu]g./day.) Four similarly injd. rabbits exposed to room daylight excreted after the same period an avg. of approx. 300 [mu]g. daily. Irradiation of 3 other Pb-poisoned rabbits with unfiltered light from a CH-4 mercury arc lamp resulted in over 100% increases in urinary coproporphyrin excretion. Normal rabbits showed no change in urinary coproporphyrin following such irradiation.

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