Evolutionary changes in the genetic code
- 23 July 1990
- journal article
- research article
- Published by The Royal Society in Proceedings Of The Royal Society B-Biological Sciences
- Vol. 241 (1300) , 19-28
- https://doi.org/10.1098/rspb.1990.0060
Abstract
The genetic code has been influenced by directional mutation pressure affecting the base composition of DNA, sometimes in the direction of increased GC content and at other times, in the direction of AT. Such pressures led to changes in species-specific usages of codons and tRNA anticodons, and also in amino acid assignments of codons in mitochondria and in several intact organisms. These code changes are probably recent evolutionary events. The genetic code is not ‘frozen’, but instead it is still evolving.This publication has 26 references indexed in Scilit:
- RNA editing in plant mitochondriaNature, 1989
- Codon usage tabulated from the GenBank Genetic Sequence DataNucleic Acids Research, 1988
- Natural Variation In The Genetic-CodeAnnual Review of Genetics, 1987
- Tetrahymena thermophila glutamine tRNA and its gene that corresponds to UAA termination codon.Proceedings of the National Academy of Sciences, 1985
- An unusual genetic code in nuclear genes of Tetrahymena.Proceedings of the National Academy of Sciences, 1985
- UGA is read as tryptophan in Mycoplasma capricolum.Proceedings of the National Academy of Sciences, 1985
- Location of transcriptional control signals and transfer RNA sequences in Torulopsis glabrata mitochondrial DNA.The EMBO Journal, 1985
- A different genetic code in human mitochondriaNature, 1979
- Altered base ratios in the DNA of an Escherichia coli mutator strain.Proceedings of the National Academy of Sciences, 1967