High Frequency of Herpes Zoster in Young Hemophiliacs

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Abstract
To the Editor: Herpes zoster usually occurs in elderly or immunocompromised patients. More recently, it has been reported in homo-sexuals and patients at risk for the acquired immunodeficiency syndrome (AIDS), with and without biologic evidence of immune deficiency.1 2 3 4 5 6 We wish to report the recent occurrence of a high frequency of herpes zoster infection in a population of 259 patients with hemophilia who were followed regularly. Using blood samples stored during the past 10 years for various protocols, we were able to relate this observation to the development of antibodies specific for human immunodeficiency virus (HIV).In the past five years . . .

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