Spontaneous Deletions of Drug-Resistance Determinants from Salmonella Typhimurium in Escherichia Coli
- 1 September 1986
- journal article
- research article
- Published by Microbiology Society in Journal of Medical Microbiology
- Vol. 22 (2) , 119-123
- https://doi.org/10.1099/00222615-22-2-119
Abstract
Plasmids isolated from two different clinical isolates of Salmonella typhimurium, both resistant to the antibiotics ampicillin, tetracycline, streptomycin and chloramphenicol, were used to transform Escherichia coli. Segregation of antibiotic-resistance determinants occurred in both cases. Analysis of plasmids from one set of segregants by DNA-DNA hybridisation indicated that the segregation was due to precise deletions in the transforming plasmid.This publication has 10 references indexed in Scilit:
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