Inhibition of Protein Tyrosine Phosphorylation in T Cells by a Novel Immunosuppressive Agent, Leflunomide
Open Access
- 1 May 1995
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 270 (21) , 12398-12403
- https://doi.org/10.1074/jbc.270.21.12398
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- LEFLUNOMIDE CONTROLS REJECTION IN HAMSTER TO RAT CARDIAC XENOGRAFTSTransplantation, 1994
- Sequential Interactions of the TCR with Two Distinct Cytoplasmic Tyrosine KinasesScience, 1994
- Signal transduction by lymphocyte antigen receptorsCell, 1994
- Inhibition of the epidermal growth factor receptor tyrosine kinase activity by leflunomideFEBS Letters, 1993
- The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation.The Journal of Experimental Medicine, 1993
- Signal transduction events leading to T-cell lymphokine gene expressionImmunology Today, 1993
- Effects of leflunomide (HWA 486) on expression of lymphocyte activation markersInflammation Research, 1993
- Signal transduction through the T-cell antigen receptorTrends in Biochemical Sciences, 1992
- Leflunomide (HWA 486), a novel immunomodulating compound for the treatment of autoimmune disorders and reactions leading to transplantation rejectionInflammation Research, 1991
- Stimulation of the phosphatidyl-inositol pathway can induce T-cell activationNature, 1990