Are interspecies comparisons in the toxicity of centrally acting drugs valid without brain concentrations? A commentary

This publication has 26 references indexed in Scilit:

• Effects of short- and long-term administration of fluoxetine on the monoamine content of rat brain
  Neuropharmacology, 1992
• Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction
  Clinical Pharmacology & Therapeutics, 1992
• Fluoxetine and norfluoxetine are potent inhibitors of P450IID6‐the source of the sparteine/debrisoquine oxidation polymorphism [letter]
  British Journal of Clinical Pharmacology, 1991
• Study of human urinary metabolism of fenfluramine using gas chromatography—mass spectrometry
  Journal of Chromatography B: Biomedical Sciences and Applications, 1991
• A new method for determining allowable daily intakes*1
  Fundamental and Applied Toxicology, 1984
• Regulatory history and experimental support of uncertainty (safety) factors
  Regulatory Toxicology and Pharmacology, 1983
• Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics
  Journal of Pharmacokinetics and Biopharmaceutics, 1982
• Kinetics of fenfluramine isomers in the rat
  European Journal of Drug Metabolism and Pharmacokinetics, 1981
• The Current Status of Attempts to Predict Species Differences in Drug Metabolism
  Drug Metabolism Reviews, 1981
• Comparison of the time course of the anorectic effect of fenfluramine and amphetamine with drug levels in blood
  Journal of Pharmacy and Pharmacology, 1975