Update on Estimation of Mutation Rates Using Data From Fluctuation Experiments
- 1 October 2005
- journal article
- research article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 171 (2) , 861-864
- https://doi.org/10.1534/genetics.104.035774
Abstract
This note discusses a minor mathematical error and a problematic mathematical assumption in Luria and Delbrück's (1943) classic article on fluctuation analysis. In addition to suggesting remedial measures, the note provides information on the latest development of techniques for estimating mutation rates using data from fluctuation experiments.Keywords
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