Formation of Lithocholic Acid from Chenodeoxycholic Acid in the Rat. Bile Acids and Steroids 103.

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Abstract
Chenodeoxycholic acid-24-C14 has been injected into the cecum of bile fistula rats. 50-60% of the isotope was absorbed. Lithocholic acid comprised more than 50% of the labelled fecal acids but only traces were found in the bile. At least 8 other microbial transformation products were present. One of these was probably 3-ketocholanic acid.