A linkage study of malignant hyperthermia (MH)
- 1 March 1990
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 37 (3) , 221-225
- https://doi.org/10.1111/j.1399-0004.1990.tb03506.x
Abstract
Five German families segregating for malignant hyperthermia (MH) were tested for linkage relationships using 35 serological and biochemical markers. Slightly positive lod scores were obtained with MNS, EsD, C3 and P. The relation with the C3 locus on chromosome 19p13.3–13.2 (ž=0.72, θ= 0.11) is of some interest, since genetic linkage of MH with several polymorphic DNA markers from the 19q12–13.2 region has been reported (McCarthy et al. 1989).Keywords
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