ANTIGEN-INDUCED LYMPHOCYTE BLASTOGENESIS IN A HOOKWORM (NECATOR-AMERICANUS) INFECTION IN MAN

  • 1 January 1976
    • journal article
    • research article
    • Vol. 27  (1) , 89-92
Abstract
A lymphocyte blastogenic technique was employed to examine cell-mediated immunity in a N. americanus infection. Infective 3rd-stage larvae of N. americanus were used for antigen preparation, and lymphocyte cultures were prepared from peripheral blood taken on days 3, 17 and 51 after infection with 250 3rd-stage larvae of N. americanus. At 3 days post-infection, lymphocyte transformation was not induced; at 17 and 51 days after infection significant transformation was obtained.

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