Major Depression in Down's Syndrome
- 1 August 1989
- journal article
- research article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 155 (2) , 202-205
- https://doi.org/10.1192/bjp.155.2.202
Abstract
Five patients with trisomy 21 (Down's syndrome (DS], referred to us for evaluation of dementia, were instead found to have major depression. All had shown cognitive and behavioural deterioration and this had led to a mistaken diagnosis of Alzheimer's disease in two. We outline and contrast the features of major depression and Alzheimer's disease in DS, and suggest that electroconvulsive therapy is an effective treatment for major depression in DS.This publication has 20 references indexed in Scilit:
- Is Mania Incompatible with Down's Syndrome?The British Journal of Psychiatry, 1985
- The Presentation of Mental Illness in Mentally Retarded AdultsThe British Journal of Psychiatry, 1982
- Problem behavior and psychiatric impairment within a developmentally disabled population I: Behavior frequencyApplied Research in Mental Retardation, 1982
- Behavioural syndromes identified by cluster analysis in a sample of 100 severely and profoundly retarded adultsPsychological Medicine, 1978
- Psychiatric disorder in an adult training centre and a hospital for the mentally handicappedPsychological Medicine, 1977
- Psychosis in Mental HandicapThe British Journal of Psychiatry, 1977
- Isle of Wight Studies, 1964–1974Psychological Medicine, 1976
- SUBNORMALITY AND ITS RELATION TO PSYCHIATRYThe Lancet, 1974
- Psychoses in Adult Mental Defectives: I. Manic Depressive PsychosisThe British Journal of Psychiatry, 1972
- THE PRIMITIVE CATATONIC PSYCHOSIS OF IDIOCY1Psychology and Psychotherapy: Theory, Research and Practice, 1934