Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase
- 1 February 2008
- journal article
- research article
- Published by Elsevier in DNA Repair
- Vol. 7 (2) , 162-169
- https://doi.org/10.1016/j.dnarep.2007.09.001
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- 5-Fluorouracil Incorporated into DNA Is Excised by the Smug1 DNA Glycosylase to Reduce Drug CytotoxicityCancer Research, 2007
- Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteinsNucleic Acids Research, 2007
- Methylating Agents and DNA Repair Responses: Methylated Bases and Sources of Strand BreaksChemical Research in Toxicology, 2006
- Fluorodeoxyuridine Modulates Cellular Expression of the DNA Base Excision Repair Enzyme Uracil-DNA GlycosylaseCancer Research, 2006
- Chk1-dependent slowing of S-phase progression protects DT40 B-lymphoma cells against killing by the nucleoside analogue 5-fluorouracilOncogene, 2006
- 5-Fluoro-2′-Deoxyuridine-Induced cdc25A Accumulation Correlates with Premature Mitotic Entry and Clonogenic Death in Human Colon Cancer CellsCancer Research, 2004
- Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblastsCarcinogenesis: Integrative Cancer Research, 2004
- Uracil in DNA – occurrence, consequences and repairOncogene, 2002
- Separating Substrate Recognition from Base Hydrolysis in Human Thymine DNA Glycosylase by Mutational AnalysisJournal of Biological Chemistry, 2000
- Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: Protein mimicry of DNACell, 1995