Acanthamoeba: biology and increasing importance in human health
Top Cited Papers
- 1 July 2006
- journal article
- review article
- Published by Oxford University Press (OUP) in FEMS Microbiology Reviews
- Vol. 30 (4) , 564-595
- https://doi.org/10.1111/j.1574-6976.2006.00023.x
Abstract
Acanthamoeba is an opportunistic protozoan that is widely distributed in the environment and is well recognized to produce serious human infections, including a blinding keratitis and a fatal encephalitis. This review presents our current understanding of the burden of Acanthamoeba infections on human health, their pathogenesis and pathophysiology, and molecular mechanisms associated with the disease, as well as virulence traits of Acanthamoeba that may be targets for therapeutic interventions and/or the development of preventative measures.Keywords
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