Mutation induction and DNA adduct formation in Chinese hamster ovary cells treated with 6-nitrochrysene, 6-aminochrysene and their metabolites
- 1 June 1992
- journal article
- Published by Elsevier in Mutation Research/Genetic Toxicology
- Vol. 279 (3) , 153-164
- https://doi.org/10.1016/0165-1218(92)90062-5
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- The role of intestinal microflora in the metabolic activation of 6-nitrochrysene to DNA-binding derivatives in miceToxicology, 1990
- Metabolism of Nitro-Polycyclic Aromatic HydrocarbonsDrug Metabolism Reviews, 1990
- Comparative lung tumorigenicity of parent and mononitro-polynuclear aromatic hydrocarbons in the BLU:Ha newborn mouse assayToxicology and Applied Pharmacology, 1989
- Mutagenicity, metabolism and DNA adduct formation of 6-nitrochrysene in Salmonella lyphimuriumMutagenesis, 1989
- Metabolism of the carcinogen (3H)6-nitrochrysene in the preweanling mouse: identification of 6-aminochrysene-1, 2-dihydrodiol as the probable proximate carcinogenic metaboliteCarcinogenesis: Integrative Cancer Research, 1988
- Dose—response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo [a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassayCarcinogenesis: Integrative Cancer Research, 1988
- Identification of C8-modified deoxyinosine and N2-and C8-modified deoxyguanosine as major products of the in vitro reaction of N-hydroxy-6-aminochrysene with DNA and the formation of these adducts in isolated rat hepatocytes treated with 6-nitrochrysene and 6-aminochryseneCarcinogenesis: Integrative Cancer Research, 1987
- Dichotomy in the mutagenicity and genotoxicity of nitropyrenes: Apparent effect of the number of electrons involved in nitroreductionMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1986
- Synthesis and mutagenicity of 1-nitro-6-nitrosopyrene and 1-nitro-8-nitrosopyrene, potential intermediates in the metabolic activation of 1,6- and 1,8-dinitropyreneCarcinogenesis: Integrative Cancer Research, 1986
- 6-Nitrochrysene is a potent tumorigen in newborn miceCarcinogenesis: Integrative Cancer Research, 1985