Experimental Infection of Domestic Animals with Japanese B Encephalitis Virus.

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Abstract
Okinawan swine, goats, horses, chickens, and ducks were inoculated intraven. with large doses of Japanese B encephalitis virus. Virus was recovered from the blood of swine and ducks 24 hrs. after inoculation and probably was present in the blood of chickens for a longer period. Serious illness was observed only in the swine. All 3 of these developed signs of encephalitis. Two died, but virus was not recovered from their brains. The rise in intracerebral neutralizing and complement-fixing antibodies was studied. Both types of antibody appeared early, but the complement-fixing antibody titers more rapidly reached diagnostic levels.