The Upper Limit for the Size of the Human Antidextran Combining Site

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Abstract
Summary: With four human antidextran sera of 1,6 specificity isomaltoheptaose was not significantly better as an inhibitor than isomaltohexaose, but with a fifth antiserum the heptasaccharide was slightly better. The data indicate that in most instances the upper limit in size for most of the antibody combining sites is complementary to a hexasaccharide but that in one instance a detectable amount of antibody complementary to a heptasaccharide was found. A Russian and an American clinical dextran gave identical quantitative precipitin curves with two human antidextran sera of 1,6 specificity.
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