STUDIES IN DISORDERS OF MUSCLE
- 1 August 1951
- journal article
- research article
- Published by American Medical Association (AMA) in A.M.A. Archives of Internal Medicine
- Vol. 88 (2) , 175-190
- https://doi.org/10.1001/archinte.1951.03810080043005
Abstract
MORE than 30 years ago the proposal was made by Timme1and others2that the pathologic process in progressive muscular dystrophy was primarily endocrine. Critical review of this concept in the light of the clinical data now available and the meager metabolic data concerning such patients in the literature yields only tenuous support for it.3Nonetheless, in initiating a long term study of the disorder, it seemed desirable to reevaluate this thesis with the aid of some of the more recently developed, as well as the older, clinical signs and laboratory tests of endocrine function. In addition to these studies of endocrine function, a number of other determinations related to metabolic processes have been carried out. The levels of serum protein have been determined and the serum proteins fractionated into various components by chemical and physical means. Meldolesi4and Stefanutti5claimed that there is presentThis publication has 0 references indexed in Scilit: