A DOUBLE BLIND TRIAL OF EXTRA‐AMNIOTIC OESTRIOL AND PROSTAGLANDIN F GELS IN CERVICAL RIPENING

Abstract
Forty nulliparous patients with a Bishop score of 3 or less were given 15 mg oestriol gel, 10 mg PGF gel or gel alone via the extra‐amniotic route. Both the oestriol and prostaglandin treated patients had a significant increase in Bishop score and a significant reduction in induction‐delivery interval compared to con‐trols. Oestriol gel had significantly less stimulatory effect on uterine activity than prostaglandin gel, indicating a possible local action.