BLASTOGENIC RESPONSE OF RABBIT LYMPHOCYTES STIMULATED WITH AUTOLOGOUS CELLS
- 1 January 1979
- journal article
- research article
- Vol. 36 (3) , 375-380
Abstract
Rabbit WBC [white blood cells] and spleen cells responded with marked blastogenesis and mitosis when cultured with mitomycin-C treated autologous sacculus rotundus, appendix and Peyer''s patches cells in the 1-way rabbit mixed leukocyte reaction (MLR). A lesser response was observed using stimulating cells of the other lymphoid organs. The blastogenic response in the 1 way autologous MLR cannot be attributed to mitogenic factors released from the mitomycin-C treated stimulator cells since it is also observed in the 2-way autologous MLR, using untreated stimulator cells. Several explanations were proposed to account for the autologous MLR.This publication has 17 references indexed in Scilit:
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