Observations on the Gya and Hy Antigens and the Antibodies that Define Them
- 6 May 1975
- journal article
- Published by Wiley in Transfusion
- Vol. 15 (3) , 270-274
- https://doi.org/10.1046/j.1537-2995.1975.15375160364.x
Abstract
Two high frequency antigens, Hy (Holley) and Gy-a (Gregory), show an apparent association. All individuals lacking Gy-a are whites and these individuals are Hy-negative. A second group of Hy-negative individuals are blacks. All of these react weakly with anti-Gy-a. Neither Gy-a nor Hy are well developed on cord cells, although antibodies to both factors have been stimulated by pregnancy. Anti-Gy-a and anti-Hy antibodies react best in the antihuman globulin test. These antibodies have low avidity, high titers, and have been implicated as causing transfusion reactions.Keywords
This publication has 3 references indexed in Scilit:
- Scoring of Hemagglutination ReactionsTransfusion, 1972
- A New Public Antigenic Determinant Gya (Gregory)Transfusion, 1967