Disturbances in collagen synthesis in trisomic cells from spontaneously aborted embryos
- 1 January 1984
- journal article
- case report
- Published by Springer Nature in Human Genetics
- Vol. 68 (3) , 269-271
- https://doi.org/10.1007/bf00418401
Abstract
Collagen synthesis in cells with trisomy 7 and 9 derived from human spontaneous abortuses was found to be lower (5.06% and 5.53% respectively) than in the control diploid cells (8.80%). The ratio of collagen types (I/III) in trisomic strains did not differ from the control data while the amount of the degraded procollagen in trisomic cells was increased.Keywords
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