Results of Pharmacologic Treatment in the Malignant Carcinoid Syndrome

Publisher Website
Google Scholar
Abstract
THE patient with the malignant carcinoid syndrome is confronted with a group of uncomfortable and debilitating symptoms. These may include recurrent acute flushing, colicky abdominal pains, violent and profuse watery diarrhea, tachycardia, asthma-like wheezing and, less often, profound weakness, depression or agitation, dyspnea and dependent edema. Rarely, joint stiffness and a peculiar sclero-dermalike constricting involvement of the integument have been noted.1 2 3 In spite of this the immediate prognosis is not necessarily poor. Thorson4 reported a survival rate of 67 per cent after one year and 50 per cent after three years in patients with metastatic disease. In the absence of . . .