MODERN IDEAS ON CHROMOSOME STRUCTURE
- 1 January 1976
- journal article
- review article
- Vol. 11 (1) , 5-13
Abstract
The structural element of an eukaryotic chromosome is the chromatin fiber. It is a DNA-protein complex of about 100-200 .ANG. thickness and most probably running through from one end of a chromatid to the other. The fine structure of this DNA-protein fiber suggests a core of globular histone subunits around which the DNA-molecule is wound. The single strandedness of chromatids is suggested by the structure of premature condensed chromosomes. The coarse G-banding seen in metaphase chromosomes is presumably caused by groups of much finer bands seen in decondensed chromosomes. The number of such fine bands in the human genome is estimated to be 10,000-100,000, figures which are in the range of the number of genes in man.This publication has 4 references indexed in Scilit:
- ELECTRON MICROGRAPHIC STUDIES OF THE EXPANDED AND UNCOILED CHROMOSOMES FROM HUMAN LEUKOCYTES*Annals of the New York Academy of Sciences, 2006
- Chromosome fibers studied by a spreading techniqueChromosoma, 1966
- The electron microscopy of unsectioned human chromosomesAnnals of Human Genetics, 1962
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