G-IMMUNOGLOBULIN, A-IMMUNOGLOBULIN AND M-IMMUNOGLOBULIN LEVELS IN PARTURIENTS BLOOD-SERUM, UMBILICAL BLOOD OF THEIR NEONATES AND THE AMNIOTIC-FLUID IN PHYSIOLOGICAL DELIVERIES
- 1 January 1984
- journal article
- research article
- Vol. 32 (1) , 127-134
Abstract
The present investigation determined the IgG, IgA and IgM concentration levels in the serum of parturients, umbilical blood of their neonates and in the amniotic fluid in 50 women with physiological pregnancy and delivery whose neonates were fully mature. In order to evaluate the IgG, IgA and IgM concentration in the biological fluids, the method of passive hemagglutination inhibition was applied. IgG and IgA were detected in all 3 environments, while the presence of IgM was confirmed in all cases in the serum but only in 78% of the tested samples of the amniotic fluid. Mean values of IgG and IgM concentration both in the parturient serum as well as in the umbilical blood of their neonates as compared with the values found in the amniotic fluid, revealed statistically significant differences. The statistically significant correlation noted between the values of the IgG concentration in the parturient serum and the umbilical blood of their neonates was not confirmed in the case of IgA and IgM.This publication has 5 references indexed in Scilit:
- Human placentae membrane receptor for IgG—i. Studies on properties and solubilization of the receptorMolecular Immunology, 1981
- Detectability and pattern of immunoglobulins in normal amniotic fluid throughout gestationAmerican Journal of Obstetrics and Gynecology, 1978
- Fetal immune response following prematurely ruptured membranesAmerican Journal of Obstetrics and Gynecology, 1976
- Elevated Cord Macroglobulins in the Diagnosis of Intrauterine InfectionsNew England Journal of Medicine, 1966
- THE IMMUNOLOGICAL DEVELOPMENT OF THE HUMAN FETUSThe Journal of Experimental Medicine, 1965