Sulfhydryl Groups and the Monodeiodination of Thyroxine to Triiodothyronine
- 24 February 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 199 (4331) , 904-906
- https://doi.org/10.1126/science.622575
Abstract
Sulfhydryl reagents exert a profound influence on the monodeiodination of thyroxine to triiodothyronine by rat and sheep tissues in vitro. A marked dithiothreitol-induced increase in the monodeiodination by fetal sheep liver homogenates suggests that the characteristically low conversion in fetal tissues is related more to the status of sulfhydryl groups than to a deficiency of the monodeiodinating enzyme.This publication has 13 references indexed in Scilit:
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