Evidence for a cellular gene with potential oncogenic activity in plants.
- 1 April 1986
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 83 (8) , 2492-2495
- https://doi.org/10.1073/pnas.83.8.2492
Abstract
During tumor inception in crown gall disease, a portion of the tumor-inducing (Ti) plasmid, the transferred DNA (T-DNA) is integrated into the genome of the plant cell. Autonomous growth of the transformants requires expression of genes in the tmr and tms regions of the T-DNA, which code for enzymes concerned with biosynthesis of the plant growth hormones cytokinin and auxin, respectively. We show that a mutation of the Habituated leaf gene, Hl, of tobacco can compensate for a defective tmr locus in expression of the tumor phenotype. This provides evidence that a specific host-cell gene hs an oncogenic function similar to tmr in the T-DNA.This publication has 37 references indexed in Scilit:
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