Onset of Progeny Immunity against Viral Arthritis/Tenosynovitis after Experimental Vaccination of Parent Breeder Chickens and Cross-Immunity against Six Reovirus Isolates

Abstract
Immunization of breeder chickens by eyedrop with viral arthritis/tenosynovitis vaccine strain S1133 (73rd egg passage) gave no immunity against day old oral challenge of their progeny at 1 wk postvaccination of breeders; progeny immunity was observed at 3, 4, 5, 6 and 7 wk postvaccination. Oral cross-challenge of immune progeny with viral isolates from Connecticut, West Virginia, California, Indiana, Pennsylvania and Minnesota, USA, showed that in vitro neutralization of an isolate by antiS1133 antiserum correlated with in vivo immunity of the progeny against oral day old challenge with such an isolate.

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