Transmitter Sensitivity of Neurons Assayed by Autoradiography
- 22 May 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 212 (4497) , 929-930
- https://doi.org/10.1126/science.6262911
Abstract
Ionic conductance channels that are opened by activating nicotinic acetylcholine receptors at synapses of sympathetic neurons are permeable to small organic amines. Uptake of a tritium-labeled amine through these channels can be measured by autoradiography. This provides a simple and direct way to assess the sensitivity of individual neurons to acetylcholine without using microelectrodes.This publication has 6 references indexed in Scilit:
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