The protective effect of inhaled BRL 10833 on allergen induced bronchospasm
- 1 September 1976
- journal article
- research article
- Published by Wiley in Clinical and Experimental Allergy
- Vol. 6 (5) , 463-469
- https://doi.org/10.1111/j.1365-2222.1976.tb01930.x
Abstract
BRL 10833, a nitroindanedione with similar inhibitory activities to DSCG [disodium chromoglycate] in immediate type IgE [immunoglobulin E] mediated hypersensitivity in the rat, was shown, when inhaled in a dose of 40 mg, to protect against allergen [Dermatophagoides pteronyssinus, grass pollen] induced bronchospasm. A significant protective effect of BRL 10833 on the immediate bronchial reaction was seen in 5 of 10 patients. A single inhalation of 40 mg BRL 10833 seems to have some protective effect on the late bronchial reaction, following an immediate reaction.This publication has 9 references indexed in Scilit:
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