Natural killing and antibody-dependent cytotoxicity by lymphocyte subpopulations in young and aging humans
- 1 July 1981
- journal article
- research article
- Published by Springer Nature in Journal of Clinical Immunology
- Vol. 1 (3) , 141-148
- https://doi.org/10.1007/bf00922755
Abstract
Natural killer (NK) and antibody-dependent cellular cytotoxicity (ADCC) were examined in the peripheral blood lymphocytes and their major subpopulations from young and aging subjects. Monocyte-depleted unseparated lymphocyte-mediated NK activity (against cells of K-562) and ADCC (against IgG-coated chicken erythrocytes) were comparable between young and aging subjects. Similarly no significant difference was observed in T cell-mediated NK and ADCC and non-T cell-mediated ADCC between young and aging subjects. Non-T cell-mediated NK activity, however, was significantly (PPPγ cells and T-cell NK or ADCC activity.This publication has 48 references indexed in Scilit:
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