A Microfluidic Approach for Screening Submicroliter Volumes against Multiple Reagents by Using Preformed Arrays of Nanoliter Plugs in a Three‐Phase Liquid/Liquid/Gas Flow
- 21 April 2005
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 44 (17) , 2520-2523
- https://doi.org/10.1002/anie.200462857
Abstract
Plugging a gap in screening: Arrays of nanoliter‐sized plugs of different compositions can be preformed in a three‐phase liquid/liquid/gas flow. The arrays can be transported into a microfluidic channel to test against a target (see schematic representation), as demonstrated in protein crystallization and an enzymatic assay.Keywords
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