Lactic and Malic Dehydrogenases in Human Fetal Tissues

26 October 1962

journal article
research article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 138 (3539) , 509-510
https://doi.org/10.1126/science.138.3539.509

Abstract

The nonparticulate fraction of homogenates of heart, liver, kidney, lung, and cerebral cortex from human fetuses of varying gestational ages was subjected to electrophoresis on starch grains. Five lactic dehydrogenases and two malic dehydrogenases with characteristic rates with pyridine nucleotide analogs were found in all tissues at all ages. Quantitative differences in the relative proportions of these peaks were observed as gestation proceeded.

Keywords

This publication has 15 references indexed in Scilit:

EVOLUTION AND DIFFERENTIATION OF DEHYDROGENASES*
Annals of the New York Academy of Sciences, 1961
LACTIC DEHYDROGENASE ISOZYMES AND THEIR DISTRIBUTION IN NORMAL TISSUES AND PLASMA AND IN DISEASE STATES*
Annals of the New York Academy of Sciences, 1961
IMMUNOCHEMICAL STUDIES OF FUNCTIONALLY SIMILAR ENZYMES*
Annals of the New York Academy of Sciences, 1961
CHROMATOGRAPHIC DIFFERENTIATION OF LACTATE DEHYDROGENASE OF HUMAN TISSUE AND SERUM*
Annals of the New York Academy of Sciences, 1961
SIGNIFICANCE OF THE HETEROGENEITY OF LACTIC DEHYDROGENASE ACTIVITY IN HUMAN TISSUES*
Annals of the New York Academy of Sciences, 1961
Lactic dehydrogenases of the developing cerebral cortex and liver of the mouse and guinea pig
Developmental Biology, 1960
Starch electrophoresis
Chromatographic Reviews, 1960
DPN‐DEPENDENT ENZYMES IN SERUM*
Annals of the New York Academy of Sciences, 1958
THE HETEROGENEITY OF LACTIC AND MALIC DEHYDROGENASE*
Annals of the New York Academy of Sciences, 1958
FURTHER STUDIES OF THE FRACTIONATION OF LACTIC DEHYDROGENASE OF BLOOD
Annals of the New York Academy of Sciences, 1958