Acquired Vitamin K-Dependent Carboxylation Deficiency in Liver Disease
- 30 July 1981
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 305 (5) , 242-248
- https://doi.org/10.1056/nejm198107303050502
Abstract
γ-Carboxyglutamic acid residues on prothrombin are synthesized from glutamic acid on a prothrombin precursor in the liver through a vitamin K-dependent carboxylase. In the absence of vitamin K or in the presence of vitamin K antagonists, an inert form of prothrombin — abnormal prothrombin — circulates in the blood.This publication has 28 references indexed in Scilit:
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