Increased Incidence of Cardiovascular Disease in Castrated Women

Publisher Website
Google Scholar
Abstract
IT was shown in a previous study from this laboratory that women who had undergone premenopausal bilateral oophorectomy subsequently experienced an increased incidence of atherosclerotic cardiovascular disease.1 This was observed on a follow-up examination that took place on an average of eleven years after surgery. These clinical findings were confirmed by Oliver and Boyd.2 Extensive postmortem studies by Ackerman et al.3 and Wuest, Dry and Edwards4 also demonstrated this relation of early castration and severity of atherosclerosis.The purpose of the present investigation was to determine possible differences in the clinical course between the two study groups: those who had . . .