7α- and 17α-Substituted estrogens containing tridentate tricarbonyl rhenium/Technetium complexes: synthesis of estrogen receptor imaging agents and evaluation using microPET with technetium-94m
- 17 November 2003
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 11 (23) , 4977-4989
- https://doi.org/10.1016/j.bmc.2003.09.004
Abstract
No abstract availableKeywords
This publication has 61 references indexed in Scilit:
- Synthesis of 2,16α- and 4,16α-difluoroestradiols and their 11β-methoxy derivatives as potential estrogen receptor-binding radiopharmaceuticalsJournal of the Chemical Society, Perkin Transactions 1, 2002
- Synthesis of 2-[18F]Fluoroestradiol, a Potential Diagnostic Imaging Agent for Breast Cancer: Strategies to Achieve Nucleophilic Substitution of an Electron-Rich Aromatic Ring with [18F]F-The Journal of Organic Chemistry, 1998
- Oxohexestrol derivatives labeled with fluorine-18. Synthesis, receptor binding and in vivo distribution of two non-steroidal estrogens as potential breast tumor imaging agentsNuclear Medicine and Biology, 1994
- The synthesis of 7α-methyl-substituted estrogens labeled with fluorine-18: potential breast tumor imaging agentsSteroids, 1994
- 16β-[18F]fluoromoxestrol: A potent, metabolically stable positron emission tomography imaging agent for estrogen receptor positive human breast tumorsLife Sciences, 1993
- 16.beta.-([18F]Fluoro)estrogens: systematic investigation of a new series of fluorine-18-labeled estrogens as potential imaging agents for estrogen-receptor-positive breast tumorsJournal of Medicinal Chemistry, 1993
- A synthesis of 7α-substituted estradiols: synthesis and biological evaluation of a 7α-pentyl-substituted BODIPY fluorescent conjugate and a fluorine-18-labeled 7α-pentylestradiol analogSteroids, 1993
- Synthesis, radiolabeling and tissue distribution of 11β-fluoroalkyl- and 11β-fluoroalkoxy-substituted estrogens: Target tissue uptake selectivity and defluorination of a homologous series of fluorine-18-labeled estrogensNuclear Medicine and Biology, 1993
- 11.beta.-Methoxy-, 11.beta.-ethyl, and 17.alpha.-ethynyl-substituted 16.alpha.-fluoroestradiols: receptor-based imaging agents with enhanced uptake efficiency and selectivityJournal of Medicinal Chemistry, 1990
- (2∗, 3∗)-1- [18fluoro-2, 3-bis (4-hydroxyphenyl) pentane ([18F]fluoronorhexestrol), A positron-emitting estrogen that shows highly-selective, receptor-mediated uptake by target tissues in vivoLife Sciences, 1983