AMNIOTIC-FLUID COMPOSITION IN NORMAL BABOON PREGNANCIES

  • 1 January 1984
    • journal article
    • research article
    • Vol. 29  (2) , 129-132
Abstract
To compare the chemical composition of baboon and human amniotic fluid, 70 amniotic fluid samples were obtained from 58 normal baboon pregnancies at times ranging from 88-178 days (term, 180 days). Protein content averaged (.+-. SE) 0.67 .+-. 0.26 g/dl, osmolality averaged 263 .+-. 1.1 mosmol/kg, and pH averaged 7.74 .+-. 0.034 U. These variables were not affected by length of gestation. Creatinine content increased parabolically with duration of gestation (r = 0.74; P < 0.001). Of the samples 40% had .DELTA.OD450 values of 0; the others had .DELTA.OD450 values ranging from 0.002-0.145. No decline in .DELTA.OD450 with gestational maturity was evident. Evidently, the chemical environment of the baboon fetus is similar but not identical to that of the human fetus.

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