Action of 3,3 Methylenebis (4-Hydroxycoumarin) (Dicumarol) on Thromboplastic Activity of Rabbit Brain.
- 1 January 1947
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 64 (1) , 47-50
- https://doi.org/10.3181/00379727-64-15694
Abstract
Thromboplastin, prepared from the brains of rabbits severely poisoned with dicumarol, shows a lower potency as measured by the one-stage method of Quick than that obtained from normal animals. This difference is accentuated by using a CaCl2 soln. which is more dilute than the standard soln. (0.02 M) routinely employed in the pro-thrombin detn. The same difference in thromboplastin activity is observed when tested on plasma obtained from dicumarolized animals[long dash]the effect of varying the concn. of Ca remains the same.Keywords
This publication has 4 references indexed in Scilit:
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- THE EFFECT OF CALCIUM CONCENTRATION ON THE PROTHROMBIN TIME OF DOGS TREATED WITH DICUMAROLAmerican Journal of Physiology-Legacy Content, 1945
- THE EFFECT OF DICUMAROL (3,3'-METHYLENEBIS [4-HYDROXYCOUMARIN]) ON PLATELET ADHESIVENESSAmerican Journal of Physiology-Legacy Content, 1944